GET THE APP

Comparision of Anti-diabetic Activity of Plant Based and Synthetic Aryltetalin Derivatives | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Abstract

Comparision of Anti-diabetic Activity of Plant Based and Synthetic Aryltetalin Derivatives

Author(s): Chaitramallu M*, Parvathi G R, Sindhu GM and Ranjini P

The aryltetralin compound podophyllotoxin was extracted from the roots of plant P. peltatum and analogues of aryltetralin were synthesized using tetralone as a starting material. They were synthesized by replacing 1, 3‐methylene dioxy ring with dimethoxy, hydroxy, methyl, chlorine and hydrogen and methoxy group. The structure of the final compounds was confirmed by 1H NMR, 13C NMR, mass spectra and elemental analysis data and the analogues were screened for anti-diabetic activity. It is noteworthy that, all the synthesized derivatives exhibits good anti-diabetic activity with respect to standard reference.


Full-Text PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 15261

Der Pharma Chemica received 15261 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry