Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Abstract
Chitosan/Polyvinyle Alcohol with Silver Nanoparticles for Antimicrobial Applications
Author(s): A. M. Hezma, A. M. Abdelghany,M. S. Abdel-Aziz and I. S. ElashmawiAn in-situ preparation technique was used for preparation of equimass samples (chitosan/poly vinyl alcohol, CS/PVA) embedded with silver nanoparticles (AgNPs). X-ray diffraction scans (XRD) showed the appearance of two new peaks with increasing silver content. XRD showed that the intensity of the peak 2q = 18.6° slightly decreased after adding AgNPs indicating that strong interaction occurred between PVA and CS and an increase in the amorphous phase in the polymeric matrices. Fourier transform infrared spectra (FTIR) showed the main characteristic bands corresponding to the polymeric constituents (CS/PVA). The UV/vis. absorption spectra and XRD scans revealed the presence of the semi-crystalline nature of the polymeric composites. The obtained polymer nano-composites were also examined for their antibacterial effect against Gram +Ve, Gram -Ve and spore forming bacteria. The nano-composite samples showed better film properties than that of the pristine polymer blends without silver nanoparticles.
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