Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Abstract
Chemical constituents of Raphanus sativus
Author(s): Consolacion Y. Ragasa 1,2* , Virgilio D. Ebajo Jr. 1 , Maria Carmen S. Tan 1 , Robert Brklja Ãâàa 2 and Sylvia Urban 3Chemical investigation of the dichloromethane extra ct of the freeze-dried roots of Raphanus sativus af forded 3-(E)- (methylthio)methylene-2-pyrrolidinethione ( 1 ), a mixture of 4-methylthio-3-butenyl isothiocyana te ( 2 ) and 4- (methylthio)butyl isothiocyanate ( 3 ), β -sitosterol ( 4 ), β -sitosteryl-3 β -glucopyranoside-6'-O-palmitate ( 5 ), monoacylglycerols ( 6 ), and a mixture of α -linolenic acid ( 7 )and linoleic acid ( 8 ). The structures of 1 - 3 were elucidated by extensive 1D and 2D NMR spectroscopy, while those of 4 - 8 were identified by comparison of their NMR data with those reported in the literature
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