Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Abstract
Chemical constituents from the rhizomes of Curcuma aromatica Salisb
Author(s): S Ahmad, M Ali, SH Ansari and F AhmedCurcuma aromatica Salisb. (Zingiberaceae) is a perennial herb found throughout India. Its rhizomes are substituted for turmeric and used externally to treat bruises, sprains, skin eruptions, infections and to improve complexion. Phytochemical investigation of the methanolic extract of the rhizomes yielded three new homosesterterpenoids characterized as 5, 9, 13, 17, 20- pentamethyl-n-heneicos-cis-3-en-6b, 7b, 8b-triol (curcusesterterpene A); 5, 9, 13, 17, 20- pentamethyl-n- heneicos-cis-6-en-2b,4b,5a-triol (curcusesterterpene B); 5, 9, 13, 17, 20- pentamethyl-n-heneicos-cis-3-en-6β, 7β, 9α-triol (curcusesterterpene C) along with the known compounds n-nonacosan-1-ol and curcumin. The structures of these phytoconstituents have been elucidated on the basis of structural data analysis and chemical reactions.
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