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Catalysis by cellulose sulfuric acid as a bio-supported and recyclable solid acid: Synthesis of 3-substituted indoles through Michael addition | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Abstract

Catalysis by cellulose sulfuric acid as a bio-supported and recyclable solid acid: Synthesis of 3-substituted indoles through Michael addition

Author(s): Surendra Bose Bathulaa, K. Mukkantia, Hariharakrishnan Venkatasubramanian

Michel addition of indoles with olefins in the presence of cellulose sulfuric acid as catalysts afford the corresponding 3-substituted indoles in excellent yields and short reaction times is described. The reaction work up is simple and the catalyst can be easily separated from the reaction mixture and reused in subsequent reaction.


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