Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
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Abstract
Anti-implantation Activity of the Leaf Extract of Bauhinia acuminata Linn
Author(s): Mohsin J. Jamadar*, Preeti Khulbe and Shrinivas K. MohiteBauhinia acuminata Linn or its local name “Dwarf White Orchid”, “TapakKuda” or “Safed Kachnar” belong to family Caesalpiniaceae is a recent medicinal plant discovered which has been employed by the folks in treating of different types of ailment such as this plant is used to treat acute and chronic pain, skin ailments, cancer, diabetes, throat infections and asthma. As there were no scientific reports on use of Bauhinia acuminata for anti-fertility activity, the present study was designed to evaluate Anti-fertility potential of aqueous and alcoholic extracts of Bauhinia acuminata Linn. Acute toxicity was carried out as per OECD guideline 423 was found safe up to of 2000 mg/kg. Anti-implantation activity of ethanolic extract of Bauhinia acuminata Linn. At doses of 200 mg/kg and 400 mg/kg, orally. Standard Ethinyl estradiol (1 mg/rat per day) was used. Among the two extracts tested at two different doses, the ethanolic extract of Bauhinia acuminata Linn. At 400 mg/kg was found to exhibit anti-fertility activity may be due to rich presence of glycoside, flavonoids, saponins and phenolic compound.
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Citations : 15261
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