In the present study, Schiff bases have been synthesized by the condensation of Trimethoprim with p-Chlorobenzaldehyde and Vanillin respectively in methanol. Further their metal complexes have been synthesized by metal salts of Mn (II), Co (II), Ni (II) and Zn (II). Structural assignment of these compounds has been made on the basis of molecular weight, molar conductivities, elemental analysis, UV, IR and 1HNMR spectral data. Synthesized compounds were screened for their in vitro growth inhibiting activity against different strains of bacteria viz., gram positive Staphylococcus aureus, Bacillus licheniformis, Micrococcus luteus and gram negetive Escherichia coli and were compared with the standard antibiotic oflaxocin
Select your language of interest to view the total content in your interested language
Der Pharma Chemica received 15261 citations as per Google Scholar report