Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
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Abstract
An enviornmentally benign one-pot synthesis of 3-aryl-furo[3,2-c]coumarins in PEG-400 and water
Author(s): Devendra S. Wagare, Dinesh Lingampalle, Mazhar Farooqui and Ayesha DurraniA Facile, ecofriendly, one-pot protocol for the synthesis of substituted 3-phenyl-furo[3,2-c]coumarins from in-situ generated α-halo ketones and 4-hydroxy coumarins in PEG-400 and water as a greener solvent. The developed protocol provides the better alternative to the existing method as it involves utilization of in-situ generated α-halo ketones and avoids the use of lachrymatric α-haloketones as well as toxic organic solvents.
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Citations : 15261
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