Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
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Abstract
An efficient synthesis of formyl coumarins by microwave irradiation methodduff formylation
Author(s): Omprakash S. Chavan, S. B. Chavan and M. A. BaseerA series of formyl derivatives of Coumarins have been synthesized by Duff formylation method, in this method hydroxyl Coumarins was reacted with hexamethylene tetramine (HMTA) in presence of tri-fluoroacetic acid (TFAA) under microwave irradiation techniques. The structures of all synthesized compounds were confirmed by IR, NMR, Mass and CHN analysis. This is a newly developed efficient synthesis of formyl Coumarins under microwave irradiation technique by Duff formylation method.
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Citations : 15261
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