Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
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Abstract
An Efficient, Greener synthesis of 2-Aryl-1-Arylmethyl-1HBenzimidazoles using Polystyrene Sulfonic acid as a Catalyst
Author(s): Prasad P. Patil, Madhukar B. Deshmukh, Abhijeet G. Mulik, Dattatraya R. Chandam, Dayanand R. Patil, Suryabala D. Jagdale, Prashant V. Anbhule, Dadasahe K. Salunkhe, Sandeep A. SankpalIncorporation of polymer supported PSSA as catalyst renders excellent chemoselectivity in the synthesis of 2-Aryl-1-Arylmethyl-1H-Benzimidazoles from reaction of o-phenylene diamine with several aryl aldehydes. The captivating aspects of this method are the greenness of water mediated system and efficient, selective achievement of desired product within 30 - 40 min.
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Citations : 15261
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