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A Catalyst Free Simple and Efficient One Pot Syntheis of N-benzyloxazolidinone Derivatives | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Abstract

A Catalyst Free Simple and Efficient One Pot Syntheis of N-benzyloxazolidinone Derivatives

Author(s): Mahesh Kumar A, Rapolu Venkateshwarlu, Shambhu Nath Singh, Chandra Sekhar VN, Akula Raghunadh*, Venkateswara Rao B and Vidavalur Siddaiah

An efficient and catalyst free one pot synthesis of N-benzyloxazolidinone derivatives is developed by reaction of N-benzyl-β-amino alcohol derivatives and N, N-Carbonyldiimidazole (CDI) in DMSO. A range of novel N-benzyloxazolidinone derivatives were synthesized by using this one pot methodology with good to excellent yields.


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