One pot method for green synthesis of 1,5-benzodiazepines
By Mallinath M. Langade
Malonic acid has been found to be an efficient catalyst for the synthesis of 2,3-dihydro-1 H -1,5-benzodiazepines from o-phenylenediamine and ketones. This method is simple, cheap, and environmentally-friendly and gives the benzodiazepines in excellent yield.
Key words:1,5-benzodiazepines; boric acid; solvent free condition.