Synthesis, characterization, anti-microbial study of 2-amino-N′-[(1E)-1-pyridine-2-ylethylidene]benzohydrazide and its Lanthanide(III) Complexes
By Vidhyadhar C. Havanur, Dayananda S. Badiger, Shashikala G. Ligade and Kalagouda B. Gudasi
A new hydrazone, 2-amino N′-[(1E)-1-pyridine-2-ylethylidene]benzohydrazide (Apbz) and its complexes with rare earth nitrates have been synthesized. These new complexes with the general formula of [Ln(Apbz)2 NO3] ∙2NO3 where Ln= La(III), Pr(III), Nd(III), Sm(III), Eu(III), Gd(III), Tb(III), Dy(III), and Y(III) were characterized by Spectral (IR, 1H NMR, 13C NMR, EPR, UV-Vis, mass), elemental analysis, thermal analysis and molar conductivity. All the complexes are stable in air. The results show that the ligand has coordinated in a tridentate fashion coordinating through pyridine nitrogen, azomethine nitrogen and the carbonyl oxygen.
Keywords: 2-acetylpyridine, Hydrazone, Lanthanide complexes, Anti-bacterial activity, Anti-fungal activity.