Synthesis and Characterization of condensed pyrazole derivatives
By Vetrivel Nadaraj and Senniappan Thamarai Selvi
A series of quinolines bearing pyrazole nucleus have been prepared in one pot by condensing various quinolines and semicarbazide in presence of catalytic amount of PTSA. All the synthesised compound have been characterised by their percentage yield, melting points, elemental analysis, 1H-NMR and 13C-NMR and IR spectra. These compounds have been screened for their antimicrobial activities.
Keywords: quinolines, condensation, pyrazole, antibacterial, PTSA.