Synthesis and Biological Activity of N-Aryl-N’-Heteroaryl Carbamides
By S. N. Pandeya, Vaishali Mishra, and Alka Pandey
A series of N-aryl-N’-heteroaryl carbamides were synthesized. The structure of the compounds was established by means of I. R., 1HNMR, Mass spectra and elemental analysis. All the compounds were screened for their antibacterial and antifungal activities. Compound 3e with chlorosubstitution was most active as antibacterial and antifungal with MIC of 0.075 mg/mL against E. coli and P. aruginosa.
Keywords : Carbamide, Thiazole, Thiadiazole, Antibacterial, Antifungal.