Microwave synthesis and antimicrobial activity of some N-aryl hydrazones
By Bharat Parashar, Sudhir Bharadwaj, Vinod K. Sharma, Pinki B. Punjabi
-N-arylhydrazone derivatives of N-phenyl anthranilic acid are pharmacologically active and are very useful. A number of hydrazide derivatives have been synthesized by the condensation of the hydrazide with the numbers of aromatic aldehydes and ketones in the presence of conc. hydrochloric acid as a catalyst. The reactions have been carried out under microwave irradiation. The structures of the products were confirmed by physico-chemical and spectral data like IR, NMR and Mass.
Keywords : N-phenyl anthranilic acid, hydrazone, hydrazide, microwave.