Design & synthesis of some novel 1, 2, 4-thiadiazoline derivatives and their biological activity

 

 

By S.N. Pandeya, Neelottama Maurya, A.K. Pathak

 

 

ABSTRACT

 

A series of 1, 2, 4 - thiadiazole derivatives were synthesized. The structures of these compounds were established by means of IR, 1H-NMR, 13C-NMR, Mass and Elemental analysis. All the compounds were evaluated for antimicrobial activities. Most of the compounds have shown significant antimicrobial activities when compared with standard drug.

 

 

 

 

Keywords : 1, 2, 4 - thiadiazole, antimicrobial activity

 

 

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