Determination of the protonation constants of some chalcones [(2E)-1-(substituted-methylthiophene-2-yl)-3-(substituted-pyridinyl)prop-2-en-1-ones] by the potentiometric method in nonaqueous solvents
By Fatih İslamoğlu, Asu Usta, İsmail Aksu, Nurettin Yaylı
Some Chalcones [(2E)-1-(Substituted-Methylthiophene-2-yl)-3-(pyridin-substituted-yl)prop-2-en-1-ones] derivatives were titrated with tetrabutylammonium hydroxide (TBAH) in four non-aqueous solvents (isopropyl alcohol, tert-butyl alcohol, N,N - dimethylformamide and acetonitrile ), using potentiometric method. The half neutralization potential values and the corresponding pKa values were determined for all cases.
Keywords : Tetrabutylammonium hydroxide, potentiometric method, half-neutralization potential.