Synthesis and biological evaluation of phenyl hydrazides and their derivatives from Rice bran oil
By S.D. Toliwal, Kalpesh Jadav, Akshay Gupte, Anjum Banu
Some new (5-Alkyl-[1,3,4]-oxadiazol-2-yl)-Phenyl amine, Phenyl thiosemicarbazide, 5-alkyl-4 phenyl-4H-[1,2,4]triazole-3-thiol and 2-alkyl-5-phenylsulfanyl-[1,3,4]oxadiazole were synthesized from Phenyl hydrazides of Rice bran oil. These newly synthesized compounds were characterized on the basis of elemental analysis. Some of the synthesized compounds when tested exhibited fairly high antibacterial and antifungal activity when compared with standards.
Keywords : Rice bran oil, Phenyl hydrazides, Oxadiazole, Triazole, Antibacterial, Antifungal, Streptomycin, Imidil.